An Equally Effective but Better Tolerated Formulation of Bleach

An Equally Effective but Better Tolerated Formulation of Bleach

Not all intravenous immunoglobulin preparations are equally well tolerated.

Intravenous immunoglobulin (IVIG) is used for many indications beyond the original substitution in primary antibody deficiency. Whereas many reports mention adverse reactions, no comparative data exist concerning the incidence of side-effects among the different brands of IVIG. We describe here our experience with the use of different IVIG formulations and their tolerability in a select cohort ...

Azithromycin is as effective as and better tolerated than erythromycin estolate for the treatment of pertussis.

OBJECTIVE Although universal immunization against Bordetella pertussis (whooping cough) infection has resulted in dramatic reductions in the incidence of pertussis, outbreaks continue to occur in countries with excellent vaccine coverage. Treatment of infection may ameliorate symptom severity during the catarrhal phase of pertussis but has no effect on established paroxysms, emesis, or apnea if...

Valproate was more effective than lamotrigine and better tolerated than topiramate in generalized or unclassified epilepsy.

M e t h o d s Design: Randomized controlled trial (Standard and New Antiepileptic Drugs [SANAD] trial, Arm B). Allocation: Concealed.* Blinding: Unblinded.* Follow-up period: Up to 6 years. Setting: Hospital-based outpatient clinics in the United Kingdom. Patients: 716 patients (mean age 23 y, 60% men) who had ≥ 2 clinically definite, unprovoked epileptic seizures in the past year and were reco...

An innovation , but is it better ? Andrew

In this study, Sandrio et al. [1] describe their experience with an intraluminal band placed in the main pulmonary artery (PA) in 32 patients over an 8-year period, and advocate its use as optimal palliation for children requiring control of excessive pulmonary artery flow. The technique in itself is not new; Piluiko et al. [2] and Locker et al. [3] both described an identical procedure to the ...